Ventolin HFA Aerosol With Adapter
As a bronchodilator-beta2-adrenomimetic, Ventolin has a bronchodilator effect on the smooth muscles of the bronchus. Myocardial adrenoreceptors have virtually no effect or little effect. By its action, the drug has the ability to arrest or prevent bronchospasm and reduce the resistance of the respiratory tract, and also increases the vital capacity of the lungs. When the bronchitis is chronic, the drug promotes an increase in mucociliary clearance to 36 percent. Its action is due to stimulation of mucus secretion and activation of the function of the ciliated epithelium.
Albuterol inhaler prescription: who need to buy and use it?
Albuterol is a selective β2-adrenergic receptor agonist. In therapeutic doses, it acts on the β2-adrenoreceptors of the smooth muscles of the bronchi and has a short (4 to 6 hours) bronchodilator effect on β2-adrenergic receptors with a rapid onset of action (within 5 minutes) with reversible airway obstruction.
The drug has a pronounced bronchodilator effect, preventing or arresting bronchospasm, reduces resistance in the airways. Increases the STR. Increases mucociliary clearance (with chronic bronchitis to 36%), stimulates the secretion of mucus, activates the functions of ciliated epithelium.
In recommended therapeutic doses, it does not have a negative effect on the cardiovascular system, does not cause an increase in blood pressure. To a lesser degree, in comparison with the drugs of this group, it has a positive chrono and inotropic effect. Causes the enlargement of the coronary arteries.
It has a number of metabolic effects: it reduces the concentration of potassium in the plasma, affects glycogenolysis and insulin secretion, has hyperglycemic (especially in patients with bronchial asthma) and a lipolytic effect, increases the risk of acidosis.
Albuterol should be used as a part of complex therapy:
• to stop and prevent the development of bronchospasm in patients with reversible airway obstruction (asthma, chronic bronchitis, emphysema)
• to arrest and prevent asthma attacks before a presumed seizure
Ventolin hfa ingredients
Aerosol for inhalation is dosed in the form of a suspension of white or almost white color. 1 dose of an inhaler contains albuterol (albuterol sulfate) micronized 120.5 μg 28.92 mg. Additional ingredients: propellant (1,1,1,2-tetrafluoroethane) in 1 dose - up to 75 mg, in 1 inhaler - up to 18 g. After the inhalation, no more than 20% of the dose of the active substance of the drug will reach the lower respiratory tract. The remaining drug can remain in the oral cavity, hitting the pharynx and then the gastrointestinal tract.
That part of the drug that fell into its intended use is absorbed into the blood and lung tissue, but is not metabolized there. The substance that gets into the digestive system when absorbed, immediately becomes subject to an intensive metabolic process in the liver with the formation of inactive phenolic sulfate. The active substance of Ventolin binds with plasma proteins to 10 percent.
Ventolin inhaler interactions
• albuterol should not be used with nonselective beta-blockers (for example, propranolol).
• Simultaneous administration of albuterol with MAO inhibitors is not contraindicated.
• In order to optimally reach the medicinal product in the lungs of a patient, it should be checked on its technique of inhalation of the drug.
Patients should be warned about the ability to experience a different taste compared to this with the use of a previous inhaler.
It is possible to face an increased need for bronchodilators, especially short-acting inhalants beta-2 agonists, to control the symptoms of bronchial asthma indicates exacerbation of the disease. In these cases, the treatment plan should be reviewed and the issue of the appointment of higher doses of inhaled corticosteroids or oral corticosteroid therapy should be considered.
albuterol is used with caution in the treatment of patients receiving large doses of other sympathomimetics. Like other beta-adrenergic agonists, albuterol can lead to reversible metabolic changes, such as increasing blood sugar levels. Compensation for such changes in patients with diabetes is not always possible, therefore, there are separate reports of the development of ketoacidosis in such patients. Concomitant use of corticosteroids can aggravate this condition.
Ventolin inhaler overdose
In case, if you overdose the drug, you risk facing the following adverse reactions. Signs and symptoms of albuterol overdose are transient phenomena pharmacologically mediated by stimulation of beta-adrenoceptors such as:
• low blood pressure,
• muscle tremor,
The use of large doses of albuterol can cause metabolic changes, including hypokalemia, it is necessary to monitor the potassium concentration in the blood serum.
When used in high doses, as well as with short-acting beta-agonists overdose, lactate acidosis was observed, therefore, in case of overdose, control over the increase of serum lactate and the possibility of developing metabolic acidosis.
Is Ventolin a Steroid?
Ventolin isn't a steroid. Steroid drugs are anti-inflammatory drugs based on hormones produced by the adrenal glands. Steroid drugs affect the human body as performing the following functions:
- suppressing immunity;
- having anti-inflammatory effect;
- demonstrating anti-allergic properties;
- having anti-shock effect.
However, they have side effects being not completely safe. These substances have an effect on the intracellular level, while linking with human DNA. Are able to exert a strong influence on many processes in the body. Among them, carbohydrate, fat, protein metabolism, as well as some other processes, for example, water-salt metabolism.
Anti-inflammatory steroid drugs have anti-allergic, anti-inflammatory and antipruritic effect. The funds of this group are used in the treatment of various dermatological diseases.
These include psoriasis, eczema, dermatitis, lichen, neurodermatitis and some other serious diseases. For these purposes, glucocorticoids, as a rule, are issued in the form of ointments, creams, gels. You need to know that their use without a doctor's appointment is impossible and can even become dangerous. Possible side effects such as atrophy, acne and some others. Ventolin has another principle of action.
After the inhalation, 10-20% of the dose of albuterol reaches the lower respiratory tract. The rest of the dose remains in the inhaler or is deposited in the oropharynx and then swallowed. The fraction deposited in the respiratory tract is absorbed into the lung tissue and blood, but not metabolized in the lungs. The degree of binding of albuterol with plasma proteins is 10%. When entering the systemic bloodstream, albuterol is hepatic metabolism and excreted mainly by the kidneys in unchanged form or in the form of phenolic sulfate.
Ventolin hfa price in the internet
Ventolin isn't the cheapest drug in the market but it is well-known for the effect it provides with. If you have taken a decision to buy Ventolin, then go shopping online. The price for the drug online is several times lower compared to the price of the same drug at your local store. If you want to save on Ventolin, then it is a good idea to purchase it online. The half price doesn't mean that the drug isn't safe.
It is of the high-quality. You will be able to use it whenever you feel difficulty with breathing. However, remember about the possible effects if overdosing.
The price may slightly vary but in the reputable drugstores it costs approximately $36 for 1 inhaler. If you buy several at once, you can save much. For example, the price for 1 inhaler will be $25.74 if you purchase 3 inhalers at a time while the price 1 inhaler is going to be even $23 if to buy 6 of them in one order. Take this into account if you want to save money. Buying several Ventolin aerosols with adapter you will be able to get a discount and save you money!
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