Ventolin (Albuterol) 100 mcg
Ventolin (Albuterol) 100 mcg is a selective β2-adrenoreceptor agonist. In therapeutic doses, it acts on the β2-adrenoreceptors of the smooth muscles of the bronchi and has a short (4 to 6 hours) bronchodilator effect on β2-adrenergic receptors with a rapid onset of action (within 5 minutes) with reversible airway obstruction. The drug has a pronounced bronchodilator effect, preventing or arresting bronchospasm, reduces resistance in the airways.
It increases the STR. It also increases mucociliary clearance (with chronic bronchitis to 36%), stimulates the secretion of mucus, activates the functions of ciliated epithelium. Solution for inhalation Ventolin 100 mcg cannot be swallowed or injected as injections. It is used with the help of a nebulizer - a small inhaler delivering the drug to the respiratory tract with the help of an endotracheal tube. When working with a nebulizer, a special mask is used. The room for the procedure should be well ventilated. Let's have a closer look at the mechanism of Ventolin 100 action.
How does Ventolin 100 work? What will it do for me?
You should take Ventolin 100 mcg if you have:
• Bronchial asthma: relief of symptoms of bronchial asthma when they occur; prevention of bouts of bronchospasm associated with exposure to an allergen or caused by physical exertion; use as one of the components with prolonged maintenance therapy of bronchial asthma.
• Other chronic lung diseases accompanied by reversible airway obstruction, including chronic obstructive pulmonary disease (COPD), chronic bronchitis, emphysema.
Bronchodilators should not be the only or main component of asthma therapy for unstable or severe flow. If there is no response to albuterol in patients with severe bronchial asthma, it is recommended to perform SCS therapy to achieve and maintain disease control. The lack of response to albuterol therapy may indicate the need for an urgent medical consultation or treatment.
The drug inhibits the release of mast cells from histamine, leukotrienes, PgD2 and other biologically active substances for a long time. It suppresses the early and late reactivity of the bronchi. Ventolin 100 mcg has a pronounced bronchodilator effect, preventing or relieving spasms of the bronchi, reduces resistance in the airways. The active substance increases mucociliary clearance (with chronic bronchitis to 36%), stimulates the secretion of mucus, activates the functions of ciliated epithelium.
It inhibits the release of inflammatory mediators from mast cells and basophils, in particular anti-IgE-induced histamine release, eliminates the antigen-dependent suppression of mucociliary transport and the release of neutrophil chemotaxis factor. Ventolin prevents the development of an allergen-induced bronchospasm. It may lead to a decrease in the number of beta-adrenergic receptors, incl. on lymphocytes.
It has a number of metabolic effects: it reduces the concentration of potassium in the plasma, affects glycogenolysis and insulin secretion, has hyperglycemic (especially in patients with bronchial asthma) and a lipolytic effect, increases the risk of acidosis. After the application of inhalation forms, the effect develops rapidly, the onset of the effect after 5 minutes, maximum after 30-90 minutes (75% of the maximum effect is achieved within 5 minutes), duration - 4-6 hours.
Take into account that very high doses of albuterol can lead to the development of adverse reactions, so the doctor can decide whether to increase the dose or frequency of the drug. Patients who use Ventolin 100 mcg at home should be warned that if the effect of the usual dose becomes less effective or less prolonged, you can not independently increase the dose or frequency of the drug, and you should immediately consult a doctor.
Ventolin should be used with caution in patients who have already taken high doses of other sympathomimetics. albuterol should be used with caution in patients with thyrotoxicosis. The therapy with b2-adrenergic agonists, especially when administered by parenteral or with a nebulizer, can lead to hypokalemia.
Particular caution should be exercised in the treatment of severe attacks of bronchial asthma, because in these cases, hypokalemia can be exacerbated by the simultaneous use of xanthine derivatives, glucocorticosteroids, diuretics, and also due to hypoxia. In such situations, it is necessary to monitor the potassium level in the blood serum.
Who should not take this medication?
The drug doesn't have many contraindications. Among the list of health conditions, when the drug is contraindicated, there are the following:
• Hypersensitivity to the active substance or any other component included in the preparation;
• preterm delivery;
• threatening abortion.
It should be taken with special care:
Albuterol should be used with caution in patients with thyrotoxicosis, tachyarrhythmia, myocarditis, heart defects, aortic stenosis, coronary heart disease, severe chronic heart failure, arterial hypertension, pheochromocytoma, decompensated diabetes mellitus, glaucoma.
Pregnancy and lactation: Pregnant women are prescribed a drug only if the expected benefit for the patient exceeds the potential risk to the fetus. During post-registration observation, rare cases of various developmental malformations in children, including the formation of "wolf mouth" and developmental limbs, were detected, against the background of the intake of albuterol by mothers during pregnancy.
In some of these cases, mothers took several concomitant medications during pregnancy. Due to the lack of a permanent nature of defects and the background frequency of congenital anomalies, ranging from 2 to 3%, the cause-and-effect relationship with taking the drug has not been established.
When used during pregnancy, you should be careful because it can cause tachycardia and hyperglycemia in the mother (especially if there is diabetes) and the fetus, and cause the mother to delay labor, reduce blood pressure, acute NC and pulmonary edema.
Breastfeeding period: albuterol probably penetrates into breast milk, and therefore it is not recommended to prescribe it to nursing women, unless the expected benefit for the patient outweighs the potential risk to the child. There is no evidence of whether the albuterol present in breast milk has a deleterious effect on the newborn.
What other drugs could interact with Ventolin (Albuterol) 100 mcg?
• It is not recommended to simultaneously use albuterol and nonselective beta-adrenoreceptor blockers, such as propranolol.
• Albuterol is not contraindicated in patients receiving monoamine oxidase (MAO) inhibitors.
• In patients with thyrotoxicosis, it increases the effect of stimulants of the central nervous system, tachycardia.
• Theophylline and other xanthines, when used simultaneously, increase the likelihood of developing tachyarrhythmias.
• Simultaneous administration with anticholinergics (including inhalation) may help increase intraocular pressure.
• Diuretics and glucocorticosteroids increase the hypokalemic effect of albuterol.
How to buy Ventolin inhaler 100 mcg online?
If you have been prescribed Ventolin 100 mcg, you can buy it online at a much cheaper price than you can purchase it at your local drugstore. The inhaler can be bought online without a prescription. Moreover, you can ask for analogues and generics if you are intererested in other drugs that are based on albuterol. You should read the instructions carefully in order to protect yourself from possible side effects.
Before buying the drug, you should be well-informed about the principle of its action. You should find out how to use the inhaler the right way.
Have you decided to buy Ventiolin over the counter online? Then, you are expected to take several simple steps.
Fill out an online order form, choose Ventolin inhaler 100 mcg and submit an order. You will get the answer of the drugstore's manager within seconds. You will be able to ask any questions using the live chat option provided at online drugstores.
The price will differ from the one that is asked for the same quality Ventolin at a local drugstore because internet pharmacies don't have as many expenditures as the traditional pharmacies have, which reflects on their pricing policy. If you need to buy an effective inhaler, do this online and save both time and money.
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